Figure 2
Figure 2. Thermodynamic analysis of VEGFR-2 D23 and full-length ECD binding to VEGF ligands. Top 2 rows show raw titration data of VEGFR-2 D23 and full-length ECD, respectively, with VEGF-A121, VEGF-C, and VEGF-E. Bottom row shows integrated and concentration normalized isothermograms. Solid lines represent the best fit according to the “One Set of Sites” model.

Thermodynamic analysis of VEGFR-2 D23 and full-length ECD binding to VEGF ligands. Top 2 rows show raw titration data of VEGFR-2 D23 and full-length ECD, respectively, with VEGF-A121, VEGF-C, and VEGF-E. Bottom row shows integrated and concentration normalized isothermograms. Solid lines represent the best fit according to the “One Set of Sites” model.

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