Figure 1 Linear relationship between... | American Society of Hematology

Figure 1

$Figure 1. Linear relationship between transplanted HSC dose and chimerism levels. (A) Chimerism levels within the peripheral blood Gr-1+ population and the KLS BMC-fraction 20 weeks posttransplantation in anti-CD40Ligand treated C57BL/6 CD45.1 recipients after transplantation of 10 × 106, 30 × 106, and 100 × 106 unfractionated C57BL/6 CD45.2 BMC. Data are expressed as means ± SEM of 2 experiments involving 9 mice per cell dose. (B) Chimerism levels within the peripheral blood Gr-1+ population, within the KLS BMCs and within the KLS/CD34− BMCs detected 20 weeks after transplantation in unconditioned C57BL/6 CD45.1 recipients after transplantation of 100 × 106 unfractionated C57BL/6 CD45.2 bone marrow cells. Data are expressed as means ± SEM (n = 5).$

Linear relationship between transplanted HSC dose and chimerism levels. (A) Chimerism levels within the peripheral blood Gr-1⁺ population and the KLS BMC-fraction 20 weeks posttransplantation in anti-CD40Ligand treated C57BL/6 CD45.1 recipients after transplantation of 10 × 10⁶, 30 × 10⁶, and 100 × 10⁶ unfractionated C57BL/6 CD45.2 BMC. Data are expressed as means ± SEM of 2 experiments involving 9 mice per cell dose. (B) Chimerism levels within the peripheral blood Gr-1⁺ population, within the KLS BMCs and within the KLS/CD34⁻ BMCs detected 20 weeks after transplantation in unconditioned C57BL/6 CD45.1 recipients after transplantation of 100 × 10⁶ unfractionated C57BL/6 CD45.2 bone marrow cells. Data are expressed as means ± SEM (n = 5).

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