Repartition of breakpoints on chromosome 9p arm. Location of PAX5 on chromosome 9 (left). A schematic of PAX5 genomic structure (right); rectangles represent exons. (1-6) Probes used for FISH analyses: telomeric and centromeric Dako commercial probes (1,2), RP11-344B23 (3), and RP11-244F8 (4), BACs and G248P82268A1 (5), and G248P85962F9 (6) fosmids. These probes enable localization of the breakpoint regions (gray rectangles). Histogram represents the number of patients harboring these breakpoints.