SS RBCs induce increased adhesion of both lymphocytes and monocytes to HUVECs. Lymphocytes (lymphs) and monocytes (monos) were isolated as described in “Adhesion of lymphocytes and monocytes.” Results are presented as percentage of adherent lymphocytes (A) or monocytes (B) at a shear stress of 1 dyne/cm². Error bars show SEM of 3 different experiments for both panels A and B. (A) Sham-treated SS RBCs or epi-treated SS RBCs were coincubated with isolated lymphocytes. Lymphocytes were then tested for adhesion to HUVECs. *P < .05 compared with unstimulated lymphs. (B) Sham-treated SS RBCs or epi-treated SS RBCs were coincubated with isolated monocytes. After incubation, monocytes were then tested for adhesion to HUVECs. *P < .01 compared with unstimulated monos.