Figure 2
![Figure 2. Heme degradation products in rat RBCs. Fluorescence of heme degradation products is shown for Hb incubated (12 hours, 37°C) at pO2 of 100 (normoxic) or 21 (hypoxic) mmHg (n = 4; A), Hb of RBC perfused through lungs inflated under normoxic and hypoxic conditions (n = 4; B), and Hb of nontreated and azide- (C) or cyanate- (D) treated RBCs. The endothelial DCF response is also shown for cyanate-treated RBCs (E) and perfused through lungs inflated under normoxic and hypoxic conditions (n = 3). Data are mean plus or minus SE (#P < .05 vs baseline [panels A,B, 1st bar]; *P < .05 vs hypoxic RBC [panel C, 1st bar]; **P < .05 vs hypoxic RBC [panel E, 1st bar]).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/111/10/10.1182_blood-2007-09-113902/6/zh80080818370002.jpeg?Expires=1756555525&Signature=N8ZB15JbVjE3QXoLrAGUFoqGShNtDykMJ78ivT8Y2bm47AiSWEHeTCsqUFuZ-TSR23eU8s~w2czW0-Og1rIyIXu-refnNH7BdvFsFqgLHOIyZUpkirvNAGDrhHBH3dYwgq8RB1pBmQXayr-CBQsNVDn847afYAr07UrMU0xUZI68-q254-5ZeZ84sz2dru6GEaVMYiFI1h1cGgWk5Iwm9KGqg6JNiUrL1eeKdrpMb2Hkd~31ByXNrj8bxIgwHrxzxnc8HcRpCTEhxagHcFJ9vKmxrDIJp5X4zfHfr7~vs5bCagKA91-ZfzLJ8PNs0wsr5IaVaHankLZjM189pnDebw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Heme degradation products in rat RBCs. Fluorescence of heme degradation products is shown for Hb incubated (12 hours, 37°C) at pO2 of 100 (normoxic) or 21 (hypoxic) mmHg (n = 4; A), Hb of RBC perfused through lungs inflated under normoxic and hypoxic conditions (n = 4; B), and Hb of nontreated and azide- (C) or cyanate- (D) treated RBCs. The endothelial DCF response is also shown for cyanate-treated RBCs (E) and perfused through lungs inflated under normoxic and hypoxic conditions (n = 3). Data are mean plus or minus SE (#P < .05 vs baseline [panels A,B, 1st bar]; *P < .05 vs hypoxic RBC [panel C, 1st bar]; **P < .05 vs hypoxic RBC [panel E, 1st bar]).
