Serum levels of G-CSF, IL-17, and GM-CSF are elevated in mice deficient in both L-selectin and PSGL-1. Serum levels of G-CSF (A), GM-CSF (C), and IL-3 (D) were determined by a Bio-Plex cytokine assay. Serum levels of IL-17 (B) were determined by ELISA. Data are expressed as means plus or minus SEM from 8 mice per group. *P < 0.05; **P < 0.01; ***P < .001 versus WT.