ADCC.

(A) Lymphoma cells (MCL6 in upper panel, MCL1 in lower panel) were incubated at different ratios with NK cells (squares), polynuclear leukocytes (triangles), or monocytes (circles) in the presence (closed symbols) or absence (open symbols) of 2 μg/mL rituximab. Cytotoxicity was determined by chromium release and is represented as the percentage of specific lysis of tumor cells. (B) NK cell–mediated lysis of lymphoma cells (4 MCLs, 4 DLCLs, 4FLs, 4 SLLs) and 2 NTs, in presence (NK + CD20) or absence (NK) of rituximab at the 25:1 (E/T) ratio.