LPS treatments caused accumulation of immune cells in the spleen and altered receptor expression in KO mice. (A) Neutrophil (PMN) content (cell/mL) (B) CD11b and (C) CD25 surface expression (Geometric mean of fluorescence intensity (GMFI)) in spleen samples of WT (black) and KO mice (white) with or without clopidogrel treatments. Values are expressed as Mean ± SEM (**p < 0.05; *p < 0.01; KO LPS-treated versus WT LPS treated and LPS-treated versus untreated, n=6).