Figure 1.
Platelet adhesion under high shear with and without inhibitors. (A) Micrographs of FR-PLT, 4C-PLT, and RT-PLT samples are shown for a single donor after 6 minutes of perfusion. Representative fluorescence intensity unit (FIU) traces are shown for (B) FR-PLT, (C) 4C-PLT, and (D) RT-PLT (Untreated •, PGI2 ■, and GSNO ▲). Data for (E) FIU (n=4) and (F) SC% (n=4) after 360 s are mean ± SEM (Untreated = black, PGI2= gray, and GSNO = white). The micrographs were cropped and enlarged; however image size proportionality was maintained between groups and timepoints. * p<0.05, † p<0.01, and ‡ p<0.001, and § p<0.0001
