Coilin regulated the expression of p27

(A)The expression of coilin was higher in RS4;11 cells than that in Reh cells, whereas p27 had the opposite expression pattern in the two cells.(B)The level of coilin increased when cells were treated with DNR.(C,D)The over-expression of coilin inhibited p27 expression and coilin knock-down increased the expression of p27.