ABC2 relative gene expression levels in three groups of C.krusei clinical isolates. (A) Relative levels of ABC2 mRNA in all the C.krusei clinical isolates. ABC2 gene expression levels was quantified and normalized relative to the housekeeping gene, ACT1; S, itraconazole-susceptible; SDD, itraconazole-susceptibledose dependent; R, itraconazole-resistant. (B) Log₁₀+3 fold increase of gene expression levels in three groups. (*P<0.05 in R compared with SDD; **P<0.01 in SDD with S; ***P<0.001 in R with S)