Age significantly affects ISTH-BAT in children with VWF levels 30 to 50 IU/dL. (A) Distribution of age and ISTH-BAT in 116 children enrolled in the Zimmerman Program. (B) Distribution of average scores on individual ISTH-BAT domains in the children. The error bars depict standard deviations. (C) Total ISTH-BAT scores in children according to different age quartiles (Q1, 0-4 years; Q2, 5-11 years; Q3, 12-14 years; Q4, 15-17 years). The green area indicates normal ISTH-BAT scores in children (≤2). P values are the outcomes of independent t tests. (D) Proportion of children with abnormal ISTH-BAT (≥3) according to age quartiles. The P value is the outcome of χ2test. (E) Proportion of children with ISTH-BAT scores of ≥8 according to age quartiles. The P value is the outcome of from χ2 test. CNS, central nervous system bleeding; GI, gastrointestinal.
Figure 2.

Age significantly affects ISTH-BAT in children with VWF levels 30 to 50 IU/dL. (A) Distribution of age and ISTH-BAT in 116 children enrolled in the Zimmerman Program. (B) Distribution of average scores on individual ISTH-BAT domains in the children. The error bars depict standard deviations. (C) Total ISTH-BAT scores in children according to different age quartiles (Q1, 0-4 years; Q2, 5-11 years; Q3, 12-14 years; Q4, 15-17 years). The green area indicates normal ISTH-BAT scores in children (≤2). P values are the outcomes of independent t tests. (D) Proportion of children with abnormal ISTH-BAT (≥3) according to age quartiles. The P value is the outcome of χ2test. (E) Proportion of children with ISTH-BAT scores of ≥8 according to age quartiles. The P value is the outcome of from χ2 test. CNS, central nervous system bleeding; GI, gastrointestinal.

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