Figure 3.
Comparisons of AUC, NPV, and time-dependent AUC of 3 response criteria for 6-month NRM. The AUC and the NPV of day 28 RR (red), day 28 OR (blue), and day 28 CR (orange) criteria for 6-month NRM were plotted in the JSTCT validation set for primary treatment (A), MAGIC validation set for primary treatment (B), JSTCT validation set for second-line treatment (C), and MAGIC validation set for second-line treatment (D). The 95% CIs are shown as error bars. Baseline rates of NPV are shown as horizontal dash lines. Better treatment response criteria are closer to the top right corner. Time-dependent AUC were compared between the treatment response criteria through the 2- to12-month interval in the JSTCT validation set for primary treatment (E), MAGIC validation set for primary treatment (F), JSTCT validation set for second-line treatment (G), and MAGIC validation set for second-line treatment (H).

Comparisons of AUC, NPV, and time-dependent AUC of 3 response criteria for 6-month NRM. The AUC and the NPV of day 28 RR (red), day 28 OR (blue), and day 28 CR (orange) criteria for 6-month NRM were plotted in the JSTCT validation set for primary treatment (A), MAGIC validation set for primary treatment (B), JSTCT validation set for second-line treatment (C), and MAGIC validation set for second-line treatment (D). The 95% CIs are shown as error bars. Baseline rates of NPV are shown as horizontal dash lines. Better treatment response criteria are closer to the top right corner. Time-dependent AUC were compared between the treatment response criteria through the 2- to12-month interval in the JSTCT validation set for primary treatment (E), MAGIC validation set for primary treatment (F), JSTCT validation set for second-line treatment (G), and MAGIC validation set for second-line treatment (H).

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