Figure 2.
Pathway enrichment analysis of differentially methylated genes. Results from the pathway enrichment analysis performed on the total data set of DMRs identified in MM samples compared to healthy control gDNA (A); and the DMRs with a cross-sample mean methylation value that indicates hypermethylation (B) and hypomethylation (C). The bubble plots depict the top 10 significantly enriched KEGG terms for each of the analyzed data sets. Diameter and color intensity of the circles are relative to the number of involved genes and the significance of the obtained enrichment score, respectively.