Recovery of neutrophils after CAR-T therapy depending on the BT group. (A) Median ANC over time depending on the BT group (non-CTX, intermediate CTX, and intensive CTX). Measured events per group and time point are provided in the table below. P values are shown to the right of the table and refer to comparisons of groups across time points and interactions between group and time points. Further statistical analyses using a linear mixed model are summarized in supplemental Table 8. Baseline, before LD. day 0, day of CAR-T infusion. (B) Time to neutrophil recovery depending on the BT group. The dashed lines indicate the median values. HRs, 95% CIs, and P values for group comparisons are provided below the curves. The number of patients at risk per time point are listed in the table below. (C-D) Box plots showing the ANC nadir values during the early (C) and late (D) post–CAR-T period depending on the BT group. The number of measurements per group and the P value of the group comparisons are given above. The framed numbers are the median values. The dashed lines indicate the threshold values for CTC grade 3 and grade 4 events. (E) Distribution of neutrophil recovery phenotypes (quick [light green], intermittent [yellow], and aplastic [dark red]) depending on the BT group. The P value of the group comparison is shown above. (F) Cumulative incidence curves (day 0-90) showing the time to (first) severe infection (grade ≥3) by BT group. The P value based on the Gray test and the number of patients at risk per group is provided below the curves. (G) Comparison of severe infection densities per 100 patient days for the first 90 days after CAR-T infusion between the BT groups.