T-ICAHT severity associates with transfusion burden and survival outcomes after CAR-T therapy. (A) Proportion of patients receiving PLT transfusions by early T-ICAHT grade. The shading indicates the number of PLT transfusions received within the first 30 days. (B) Proportion of patients receiving packed RBC transfusions by early T-ICAHT grade. The shading indicates the number of RBC transfusions received within the first 30 days. (C) Kaplan-Meier estimates of OS landmarked at day 30 by early T-ICAHT severity. (D) Kaplan-Meier estimates of PFS landmarked at day 30 by early T-ICAHT severity. (E) Results of the multivariable Cox regression analysis for OS landmarked at day 30. (F) Results of the multivariable Cox regression analysis for PFS landmarked at day 30. KPS, Karnofsky Performance Status; LD, lymphodepletion; LM, landmarked; PLT, platelet; ref., reference group.