Exposure-response analysis for blast count reduction in PB and BM for group I patients who received IV RO7283420. (A) Total blast count reduction. (B) Percentage blast count reduction. The dashed line represents a linear regression of the data, and the shaded area shows the corresponding 95% confidence interval. The patient marked with an asterisk (∗) has been retrospectively corrected from CR to NE. AUC, area under the curve; CR, complete remission; IV, intravenous; SD, stable disease; PD, progressive disease; NA, not available; NE, not evaluable.