Pharmacokinetic profiles of RO7283420 in group I patients during cycle 1 following different dosing regimens. (A) Fixed IV dosing. (B) SSU dosing. (C) DSU IV dosing. (D) DSU SC dosing. DSU, double step-up; IV, intravenous; Q3W, every 3 weeks; QW, every week; SC, subcutaneous; SSU, single step-up.