Morphology of the platelet-depleted blood clots right after formation and after unconstrained compaction. Representative light microscopy (A-B) and scanning electron microscopy (C-D) images of clots from platelet-depleted reconstituted blood samples before (A,C) and after (B,D) clot shrinkage over 60 minutes, showing nonaggregated (A,C) and aggregated (B,D) RBCs. Scale bars, 50 μm (A-B) and 15 μm (C-D).