Biological characteristics of TP53^mut MDS and AML. (A) Blast percent in BM and peripheral blood. (B) Oncoplot depicting comutations, associated chromosomal abnormalities, non-DBD mutations, and allelic status. Top 5 associated gene mutations are illustrated. (C) TP53^mut VAF stratified using the ICC classification. (D) Lollipop plot of the associated TP53 mutations. Most variants were in the DBD. (E) BM blast percentage stratified by single-hit or multihit TP53. Chr.5.abn, chromosome 5 abnormalities.