Figure 5.
ROR1-bispecific Teng reduce ALL viability. (A) BCP-ALL cells (Pts 16 and 19), T-ALL cells (Pts 22-24 and 26), and NBM cells (n = 4) were incubated 1:1 with T cells ± ROR1 Teng or CD19 Teng for 24 hours and cell viability assessed by flow cytometry. (B) IFN-γ release was measured in supernatants of cytotoxicity assays. Data represent mean ± SD. ∗P ≤ .05, ∗∗P ≤ .01, and ∗∗∗P ≤ .001.

ROR1-bispecific Teng reduce ALL viability. (A) BCP-ALL cells (Pts 16 and 19), T-ALL cells (Pts 22-24 and 26), and NBM cells (n = 4) were incubated 1:1 with T cells ± ROR1 Teng or CD19 Teng for 24 hours and cell viability assessed by flow cytometry. (B) IFN-γ release was measured in supernatants of cytotoxicity assays. Data represent mean ± SD. ∗P ≤ .05, ∗∗P ≤ .01, and ∗∗∗P ≤ .001.

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