CRP comparisons by sex and menstrual cycle phase. (A) No significant difference in CRP was detected in female (n = 13) vs male individuals (n = 18) with SCD. (B) CRP was significantly elevated in females in the follicular phase (FP, n = 9) compared with females in the luteal phase (LP; n = 4; P < .05). No significant difference was observed between males and females in the LP (P = .22) or females in the FP (P = .59). Analysis was performed using with the Kruskal-Wallis test to compare ranks between 3 groups.