T-cell phenotypic analysis of 19-28z CAR EBV-VSTs. (A) Dot plots comparing CD3+ T-cell subsets of paired parental EBV-VSTs with 19-28z CAR EBV-VSTs. (B) Dot plots comparing CD3+ T-cell subsets of 19-28z CAR EBV-VSTs with 19-28z CAR T cells. (C) Dot plots comparing CD3+ CAR+ T-cell subsets of 19-28z CAR EBV-VSTs vs 19-28z CAR T cells. (D) Ring graphs comparing exhaustion marker (PD1, LAG3, ICOS, and CTLA4) expression of CD3+ EBV-VSTs with 19-28z CAR EBV-VSTs. (E) Ring graphs comparing exhaustion marker (PD1, LAG3, ICOS, and CTLA4) expression of CD3+ 19-28z CAR EBV-VSTs with 19-28z CAR T cells. (F) Ring graphs comparing exhaustion marker (PD1, LAG3, ICOS, and CTLA4) expression of CD3+ CAR+ 19-28z CAR EBV-VSTs with 19-28z CAR T cells. (G) Percent expression of individual exhaustion markers (PD1, LAG3, ICOS, and CTLA4) on T-cell subsets of EBV-VSTs vs 19-28z CAR EBV-VSTs. (H) Percent expression of individual exhaustion markers (PD1, LAG3, ICOS, and CTLA4) on T-cell subsets of 19-28z CAR EBV-VSTs vs 19-28z CAR T cells. P values were determined by Mann-Whitney-Wilcoxon tests.