Impact of DZsig+ on CNS relapse in aggressive B-cell lymphoma. BL and HGBCL-DH-BCL2 are typically DZsig+ and associated with increased CNS relapse compared with DZsig− GCB-DLBCL. DZsig+ is associated with leptomeningeal relapses compared with subtypes of ABC-DLBCL.

Impact of DZsig+ on CNS relapse in aggressive B-cell lymphoma. BL and HGBCL-DH-BCL2 are typically DZsig+ and associated with increased CNS relapse compared with DZsig− GCB-DLBCL. DZsig+ is associated with leptomeningeal relapses compared with subtypes of ABC-DLBCL.

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