Figure 3.
Polynomic curve interpolation of MRD results for 3 functional gene classes with the highest number of monitored relapse mutations. EM, epigenetic modifier genes (n = 61); M, all mutations; ST, signal transduction genes (n = 54); TS, tumor suppressor genes (n = 36). See supplemental Table 8 for genes included in these categories. f(xEM)=0.98+0.4xEM+0.08xEM2+0.008xEM3−0.0004xEM4−0.0000077xEM5, f(xTS)=0.97+0.6xTS+0.2xTS2+0.02xTS3−0.001xTS4−0.00034xTS5, f(xST)=0.97+0.7xST+0.2xST2+0.03xST3−0.002xST4−0.00043xST5.

Polynomic curve interpolation of MRD results for 3 functional gene classes with the highest number of monitored relapse mutations. EM, epigenetic modifier genes (n = 61); M, all mutations; ST, signal transduction genes (n = 54); TS, tumor suppressor genes (n = 36). See supplemental Table 8 for genes included in these categories. f(xEM)=0.98+0.4xEM+0.08xEM2+0.008xEM3−0.0004xEM4−0.0000077xEM5⁠, f(xTS)=0.97+0.6xTS+0.2xTS2+0.02xTS3−0.001xTS4−0.00034xTS5⁠, f(xST)=0.97+0.7xST+0.2xST2+0.03xST3−0.002xST4−0.00043xST5⁠.

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