Figure 1.
IL-1α and -1β concentrations in the plasma of patients with TTP; correlations with troponin and PS-100b concentrations. IL-1α (A) and IL-1β (B) plasma levels quantified by ELISA in TTP nonsurvivors (n = 10), TTP survivors (n = 20), in patients with TTP in remission (n = 10), and controls (n = 10). IL-1α plasma levels in nonsurvivors: 6.65 (4.39-13.64) pg/mL; in survivors: 1.72 (0.86-4.88) pg/mL; in control: 0.08 (0-1.64) pg/mL, and in those in remission: 0.72 (0.36-1.19) pg/mL. IL-1β plasma levels in nonsurvivors: 3.51 (3.20-3.93) pg/mL; in survivors: 3.34 (3.19-3.45) pg/mL; in control: 2.55 (0.87-3.22) pg/mL; and in those in remission 2.31 (0.82-3.12) pg/mL. Correlation between troponin T and IL-1α (C), or between troponin T and IL-1β plasma levels (D) in patients with TTP. Correlation between PS-100b and IL-1α (E), or between PS-100b and IL-1β (F) plasma levels in patients with TTP (∗P < .05, ∗∗P < .01, and ∗∗∗P < .001).

IL-1α and -1β concentrations in the plasma of patients with TTP; correlations with troponin and PS-100b concentrations. IL-1α (A) and IL-1β (B) plasma levels quantified by ELISA in TTP nonsurvivors (n = 10), TTP survivors (n = 20), in patients with TTP in remission (n = 10), and controls (n = 10). IL-1α plasma levels in nonsurvivors: 6.65 (4.39-13.64) pg/mL; in survivors: 1.72 (0.86-4.88) pg/mL; in control: 0.08 (0-1.64) pg/mL, and in those in remission: 0.72 (0.36-1.19) pg/mL. IL-1β plasma levels in nonsurvivors: 3.51 (3.20-3.93) pg/mL; in survivors: 3.34 (3.19-3.45) pg/mL; in control: 2.55 (0.87-3.22) pg/mL; and in those in remission 2.31 (0.82-3.12) pg/mL. Correlation between troponin T and IL-1α (C), or between troponin T and IL-1β plasma levels (D) in patients with TTP. Correlation between PS-100b and IL-1α (E), or between PS-100b and IL-1β (F) plasma levels in patients with TTP (∗P < .05, ∗∗P < .01, and ∗∗∗P < .001).

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