Figure 2. Mechanisms through which... | American Society of Hematology

Figure 2.

Mechanisms through which HLA-DR is expressed on human neutrophils. (A) DAMPs: ox-LDL and E-CIRP.15 (B) Phagocytosis of red blood cells.23 (C) Cytokines: GM-CSF and IFN-γ.24,25 DAMPs, damage-associated molecular patterns; E-CIRP, extracellular cold-inducible RNA-binding protein; GM-CSF, granulocyte-macrophage colony-stimulating factor; IFN-γ, interferon gamma; ox-LDL, oxidized low-density lipoprotein; RBC, red blood cells. Figure made with Biorender.com.

Mechanisms through which HLA-DR is expressed on human neutrophils. (A) DAMPs: ox-LDL and E-CIRP.¹⁵ (B) Phagocytosis of red blood cells.²³ (C) Cytokines: GM-CSF and IFN-γ.²⁴^,²⁵ DAMPs, damage-associated molecular patterns; E-CIRP, extracellular cold-inducible RNA-binding protein; GM-CSF, granulocyte-macrophage colony-stimulating factor; IFN-γ, interferon gamma; ox-LDL, oxidized low-density lipoprotein; RBC, red blood cells. Figure made with Biorender.com.

This Feature Is Available To Subscribers Only