Figure 2.
Specificity of neo-T cells toward individual neoantigens. (A) Representative example from 2 donors showing IFN-γ ELISpot responses toward each of the 14 neopools individually (left; data presented as SFC per 2 × 105 input cells) and summary data for all donors (right). (B) The percentage of neo-T cell lines showing responses to 1, 2 to 3, 4 to 6, and 7 neopools. The black arc indicates the proportion of multispecific neo-T cells (ie, neo-T cells recognizing ≥2 neoantigens).

Specificity of neo-T cells toward individual neoantigens. (A) Representative example from 2 donors showing IFN-γ ELISpot responses toward each of the 14 neopools individually (left; data presented as SFC per 2 × 105 input cells) and summary data for all donors (right). (B) The percentage of neo-T cell lines showing responses to 1, 2 to 3, 4 to 6, and 7 neopools. The black arc indicates the proportion of multispecific neo-T cells (ie, neo-T cells recognizing ≥2 neoantigens).

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