Timeline of COVID-19 infection in 17 patients residing in the United States. All patients tested positive for COVID-19 via polymerase chain reaction or antigen testing. The duration of symptoms is indicated using rectangles, which are depending on whether they received COVID-19 vaccination. The timing of each SARS-CoV-2 vaccine dose is depicted using triangles. The dotted lines indicate when >95% of COVID-19 cases were caused by Delta (light gray) or Omicron (dark gray) variants, based on the Center for Disease Control variant surveillance data. Patients were grouped based on their vaccination status.