Figure 2.
Expansion of SECTM1 CAR T cells. (A) Fold change in the proliferation of NT, MOCK, and SECTM1 CAR T cells were measured by cell counting every 3 days after transduction. (B) Total number of T cells were calculated by cell counting every 3 days after transduction. (C) Data and statistical analysis results of representative CD4/CD8 expression of T cells, measured by flow cytometry on day 3 after transduction. (D) Data and statistical analysis results of naive-like (naive: CCR7+CD45RO−), central memory (CM: CCR7+CD45RO+), effector memory (EM: CCR7−CD45RO+), and effector ( CCR7−CD45RO–) T cells were measured via CD45RO and CCR7 staining by flow cytometry on day 3 after transduction. Data in panels A, B, C, and D are presented as the mean ± SD of triplicates.

Expansion of SECTM1 CAR T cells. (A) Fold change in the proliferation of NT, MOCK, and SECTM1 CAR T cells were measured by cell counting every 3 days after transduction. (B) Total number of T cells were calculated by cell counting every 3 days after transduction. (C) Data and statistical analysis results of representative CD4/CD8 expression of T cells, measured by flow cytometry on day 3 after transduction. (D) Data and statistical analysis results of naive-like (naive: CCR7+CD45RO−), central memory (CM: CCR7+CD45RO+), effector memory (EM: CCR7−CD45RO+), and effector ( CCR7−CD45RO–) T cells were measured via CD45RO and CCR7 staining by flow cytometry on day 3 after transduction. Data in panels A, B, C, and D are presented as the mean ± SD of triplicates.

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