Figure 4.
Anti-BKV T-cell activity and clinical response in patients treated with BKV-specific VSTs for active BKV infection. (A) Anti-BKV antigen (viral capsid protein 1 [VP1], large T [LgT]) T-cell response of the BKV-specific VST products as detected by IFN-γ ELISpot assay. Anti-BKV antigen T-cell response and BKV viral load (copies per milliliter) in the recipient PB post-VST infusion for patient P4 treated with BKV infection (B) and timing of concomitant standard antiviral treatment. BKV, BK virus; PCR, polymerase chain reaction; SFU, spot forming units.

Anti-BKV T-cell activity and clinical response in patients treated with BKV-specific VSTs for active BKV infection. (A) Anti-BKV antigen (viral capsid protein 1 [VP1], large T [LgT]) T-cell response of the BKV-specific VST products as detected by IFN-γ ELISpot assay. Anti-BKV antigen T-cell response and BKV viral load (copies per milliliter) in the recipient PB post-VST infusion for patient P4 treated with BKV infection (B) and timing of concomitant standard antiviral treatment. BKV, BK virus; PCR, polymerase chain reaction; SFU, spot forming units.

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