Figure 3.
Large B-cell lymphoma with 11q aberration. (A) Low power view of large-cell morphology, abundant mitoses, and the characteristic starry-sky pattern with abundant macrophages with coarse apoptotic bodies (original magnification ×200; H&E stain). (B) Higher magnification reveals the large centroblastic morphology of the tumor cells (original magnification ×400; H&E stain). Inset: FISH analysis demonstrated the typical 11q alterations (blue, centromere; red, 11q24 loss; green, 11q23 gain; ×1000). The cytology of the cells might be medium-size to large-size cells. The morphology and mutational profile justify the change in the name of this entity (previously, Burkitt-like lymphoma with 11q aberration).

Large B-cell lymphoma with 11q aberration. (A) Low power view of large-cell morphology, abundant mitoses, and the characteristic starry-sky pattern with abundant macrophages with coarse apoptotic bodies (original magnification ×200; H&E stain). (B) Higher magnification reveals the large centroblastic morphology of the tumor cells (original magnification ×400; H&E stain). Inset: FISH analysis demonstrated the typical 11q alterations (blue, centromere; red, 11q24 loss; green, 11q23 gain; ×1000). The cytology of the cells might be medium-size to large-size cells. The morphology and mutational profile justify the change in the name of this entity (previously, Burkitt-like lymphoma with 11q aberration).

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