Figure 1.
Schematic representation of CNAs in DNA of tumor cells of patients with Sz determined for independent cohorts using different platforms. Gains/amplifications are in red (on top of the x-axis) and losses/deletions in blue (below the x-axis). (A) Twenty patients using aCGH (Vermeer et al2). (B) Twenty-eight patients using single nucleotide polymorphism arrays (Caprini et al13). (C) Forty patients using NGS (Choi et al14). (D) Thirty-seven patients using NGS (Wang et al15). Location of genes recurrently affected by CNA in Sz are indicated. Irrespective of the technique/laboratory/protocol used, not only comparable aberrant chromosomal areas are identified but also with a similar frequency.

Schematic representation of CNAs in DNA of tumor cells of patients with Sz determined for independent cohorts using different platforms. Gains/amplifications are in red (on top of the x-axis) and losses/deletions in blue (below the x-axis). (A) Twenty patients using aCGH (Vermeer et al2). (B) Twenty-eight patients using single nucleotide polymorphism arrays (Caprini et al13). (C) Forty patients using NGS (Choi et al14). (D) Thirty-seven patients using NGS (Wang et al15). Location of genes recurrently affected by CNA in Sz are indicated. Irrespective of the technique/laboratory/protocol used, not only comparable aberrant chromosomal areas are identified but also with a similar frequency.

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