Relationship between A2 expression and plasmin generation. Plasmin-generating capacity (RFU/min²) is plotted against A2/GAPDH expression ratio. Samples from HCs (n = 15, blue dots), VTE with negative FH (VTE−FH, purple dots), VTE with a positive FH and an IT (VTE+FH+IT, green dots, enclosed in green oval), and VTE with a positive FH but no known IT (VTE+FH−IT, red dots, enclosed in red oval) are shown. Subjects testing positive for the 5-SNP cluster are indicated by solid black circles.