Models of pathogenesis for SCFL and PCFCL and proposed clinical prediction algorithm. (A) Proposed SCFL and PCFCL ontogenies. Solid red arrows denote sites of genetic mutational events supported by the FL literature, and dotted red arrows denote hypothesized sites. CMG, chromatin-modifying genes. (B) Proposed clinical prediction algorithm for approaching newly diagnosed cases of cutaneous follicular lymphoma.