IC50 of various antilymphoma medications for MBL2 and HUT78 cell line
Drug . | Class . | IC50 MBL2, µM . | IC50 HUT78, µM . |
---|---|---|---|
Talazoparib | PARP-1 inhibitor | 316.8 | 190 |
Bexarotene | Rexinoid | 45.7 | 16.9 |
Vorinostat | HDACi | 9.7 | 0.13 |
Romidepsin | HDACi | 0.0548 | 0.027 |
Methotrexate | Folate inhibitor | 314.7 | 38.5 |
Pralatrexate | Folate inhibitor | 115.9 | 94.5 |
Boretzomib | Proteosome inhibitor | 0.009 | 0.009 |
Drug . | Class . | IC50 MBL2, µM . | IC50 HUT78, µM . |
---|---|---|---|
Talazoparib | PARP-1 inhibitor | 316.8 | 190 |
Bexarotene | Rexinoid | 45.7 | 16.9 |
Vorinostat | HDACi | 9.7 | 0.13 |
Romidepsin | HDACi | 0.0548 | 0.027 |
Methotrexate | Folate inhibitor | 314.7 | 38.5 |
Pralatrexate | Folate inhibitor | 115.9 | 94.5 |
Boretzomib | Proteosome inhibitor | 0.009 | 0.009 |