Clinical characteristics of healthy donors and hospitalized patients with COVID-19
| Characteristics . | Healthy donors (n = 17) . | Hospitalized . | P . | |
|---|---|---|---|---|
| Non-ICU COVID-19 infection (n = 19) . | ICU COVID-19 infection (n = 14) . | |||
| Age, mean ± SD, y | 50.6 ± 17.6 | 48.2 ± 13.6 | 64.5 ± 13.7 | .008 |
| Male | 50 | 52.6 | 57.1 | .94 |
| Hispanic/Latino/African American | 11.8 | 31.6 | 42.9 | .15 |
| BMI (kg/m2), mean ± SD | 33.9 ± 9.6 | 30.5 ± 9.4 | .43 | |
| Diabetes | 31.6 | 57.1 | .15 | |
| Hypertension | 36.8 | 42.9 | .74 | |
| Chronic lung disease | 26.3 | 42.9 | .33 | |
| SOFA score, mean ± SD | 1.6 ± 1.3 | 4.6 ± 1.2 | <.0001 | |
| ARDS | 10.5 | 92.9 | <.0001 | |
| Mechanical ventilation | 0.0 | 50.0 | <.0001 | |
| 28-d survival | 100 | 71.4 | .011 | |
| WBC (k/uL), mean ± SD | 6.1 ± 2.4 | 8.3 ± 2.3 | .02 | |
| Platelet count (k/uL), mean ± SD | 245 ± 107 | 244 ± 56 | .97 | |
| Characteristics . | Healthy donors (n = 17) . | Hospitalized . | P . | |
|---|---|---|---|---|
| Non-ICU COVID-19 infection (n = 19) . | ICU COVID-19 infection (n = 14) . | |||
| Age, mean ± SD, y | 50.6 ± 17.6 | 48.2 ± 13.6 | 64.5 ± 13.7 | .008 |
| Male | 50 | 52.6 | 57.1 | .94 |
| Hispanic/Latino/African American | 11.8 | 31.6 | 42.9 | .15 |
| BMI (kg/m2), mean ± SD | 33.9 ± 9.6 | 30.5 ± 9.4 | .43 | |
| Diabetes | 31.6 | 57.1 | .15 | |
| Hypertension | 36.8 | 42.9 | .74 | |
| Chronic lung disease | 26.3 | 42.9 | .33 | |
| SOFA score, mean ± SD | 1.6 ± 1.3 | 4.6 ± 1.2 | <.0001 | |
| ARDS | 10.5 | 92.9 | <.0001 | |
| Mechanical ventilation | 0.0 | 50.0 | <.0001 | |
| 28-d survival | 100 | 71.4 | .011 | |
| WBC (k/uL), mean ± SD | 6.1 ± 2.4 | 8.3 ± 2.3 | .02 | |
| Platelet count (k/uL), mean ± SD | 245 ± 107 | 244 ± 56 | .97 | |
Unless otherwise noted, data are percentages (%).
BMI, body mass index; SOFA, Sequential Organ Failure Assessment; WBC, white blood cell count.