Table 1.

Exclusion criteria for deferred imaging and empiric rivaroxaban

Factors with a higher risk of adverse effects of rivaroxaban
Concomitant anticoagulation* 
Suspected active or recent bleeding 
Major risk factors for bleeding 
Active cancer or chemotherapy within the past 6 mo 
Pregnancy or lactation 
Hemoglobin <11 g/dL or thrombocytes <100 × 109/L 
GFR <45 mL/min per 1.73 m2 
Liver disease with coagulopathy or other bleeding risk 
Concomitant medications possibly interacting with rivaroxaban 
Factors with a higher risk of adverse effects of rivaroxaban
Concomitant anticoagulation* 
Suspected active or recent bleeding 
Major risk factors for bleeding 
Active cancer or chemotherapy within the past 6 mo 
Pregnancy or lactation 
Hemoglobin <11 g/dL or thrombocytes <100 × 109/L 
GFR <45 mL/min per 1.73 m2 
Liver disease with coagulopathy or other bleeding risk 
Concomitant medications possibly interacting with rivaroxaban 
Conditions or situations in which scheduled workup is deemed inappropriate
Suspicion of concurrent PE 
Comorbidities necessitating admission 
Suspected ischemia or eligibility for thrombolysis 
Physician considers discharge unsafe 
Patient objects to discharge 
Logistical challenges 
Workup can be completed within 2 h 
Conditions or situations in which scheduled workup is deemed inappropriate
Suspicion of concurrent PE 
Comorbidities necessitating admission 
Suspected ischemia or eligibility for thrombolysis 
Physician considers discharge unsafe 
Patient objects to discharge 
Logistical challenges 
Workup can be completed within 2 h 
*

Regular prescription or empiric anticoagulation for suspected DVT.

Current or recent gastrointestinal ulceration; presence of malignant neoplasms at high risk of bleeding; recent brain or spinal injury; recent brain, spinal, or ophthalmic surgery; recent intracranial hemorrhage; known or suspected esophageal varices; arteriovenous malformations; vascular aneurysms; major intraspinal, or intracerebral vascular abnormalities.

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