Table 3.

Risk stratification of infant ALL

RiskInterfantCOGJPLSGApproximate EFS, %
High KMT2A-r and age <6 mo and WBCs ≥ 300 000/μL KMT2A-r and age <3 mo KMT2A-r and (age <6 mo or CNS leukemia) 20 
Intermediate KMT2A-r and not high risk KMT2A-r and not high risk KMT2A-r and not high risk 50 
Low wt-KMT2A wt-KMT2A wt-KMT2A 75 
RiskInterfantCOGJPLSGApproximate EFS, %
High KMT2A-r and age <6 mo and WBCs ≥ 300 000/μL KMT2A-r and age <3 mo KMT2A-r and (age <6 mo or CNS leukemia) 20 
Intermediate KMT2A-r and not high risk KMT2A-r and not high risk KMT2A-r and not high risk 50 
Low wt-KMT2A wt-KMT2A wt-KMT2A 75 
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