Table 4.

Effect of DOACs vs LMWHs

Composite outcomeRelative effect (95% CI)Proportion of events, %
Including asymptomatic events 0.88 (0.76-1.01)  
 Asymptomatic proximal DVT 0.84 (0.70-1.01) 64.1 
 Symptomatic proximal or distal DVT 0.62 (0.36-1.05) 8.5 
 PE 0.67 (0.41-1.09) 6.6 
 Death due to DVT 0.70 (0.45-1.08) 8.3 
 Major bleeding 1.99 (1.08-3.65) 12.4 
Based only on symptomatic events 1.04 (0.67-1.60)  
 Symptomatic DVT 0.62 (0.36-1.05) 23.8 
 PE 0.67 (0.41-1.09) 31.0 
 Major bleeding 1.99 (1.08-3.65) 45.1 
Composite outcomeRelative effect (95% CI)Proportion of events, %
Including asymptomatic events 0.88 (0.76-1.01)  
 Asymptomatic proximal DVT 0.84 (0.70-1.01) 64.1 
 Symptomatic proximal or distal DVT 0.62 (0.36-1.05) 8.5 
 PE 0.67 (0.41-1.09) 6.6 
 Death due to DVT 0.70 (0.45-1.08) 8.3 
 Major bleeding 1.99 (1.08-3.65) 12.4 
Based only on symptomatic events 1.04 (0.67-1.60)  
 Symptomatic DVT 0.62 (0.36-1.05) 23.8 
 PE 0.67 (0.41-1.09) 31.0 
 Major bleeding 1.99 (1.08-3.65) 45.1 

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