Test accuracy for serial ultrasound in patients with suspected recurrent lower extremity DVT
| Test result . | No. of results per 1000 patients tested (95% CI) . | No. of participants (studies) . | Certainty of the evidence (GRADE) . | |
|---|---|---|---|---|
| Prevalence 15%*† in patients suspected of having LE DVT . | Prevalence 40%*† in patients suspected of having LE DVT . | |||
| True positives | 144 (129-149) | 384 (344-396) | 205 (1) | ⊕⊕◯◯ Low‡ |
| False negatives | 6 (1-21) | 16 (4-56) | ||
| True negatives | 850 (808-850) | 600 (570-600) | 205 (1) | ⊕⊕◯◯ Low‡ |
| False positives | 0(0-42) | 0 (0-30) | ||
| Inconclusive test results | 0 | 205 (1) | ||
| Complications arising from the diagnostic test | NA | |||
| Test result . | No. of results per 1000 patients tested (95% CI) . | No. of participants (studies) . | Certainty of the evidence (GRADE) . | |
|---|---|---|---|---|
| Prevalence 15%*† in patients suspected of having LE DVT . | Prevalence 40%*† in patients suspected of having LE DVT . | |||
| True positives | 144 (129-149) | 384 (344-396) | 205 (1) | ⊕⊕◯◯ Low‡ |
| False negatives | 6 (1-21) | 16 (4-56) | ||
| True negatives | 850 (808-850) | 600 (570-600) | 205 (1) | ⊕⊕◯◯ Low‡ |
| False positives | 0(0-42) | 0 (0-30) | ||
| Inconclusive test results | 0 | 205 (1) | ||
| Complications arising from the diagnostic test | NA | |||
An interactive version of this table is available at: https://gdt.gradepro.org/presentations/#/isof/isof_0654358c-94e7-42ba-bd06-f9805a8e32be-1582834779298?_k=qsnepk.
Patient or population: Patients with suspected recurrent lower extremity deep vein thrombosis. Setting: Inpatient and outpatient. Pooled sensitivity: 0.96 (95% CI, 0.86-0.99). Pooled specificity: 1.00 (95% CI, 0.95-1.00).
Prevalence of recurrent VTE was estimated to be 13% (1 year) to 30% (10 years) based on the review (20% used in the table).61
Clinical PTP and D-dimer used to evaluate patients with suspected recurrent DVT, prevalence 44.8% (40% used in table).56
Certainty of evidence was downgraded twice for serious imprecision given the small population size from the 2 recurrent lower extremity DVT studies identified for analysis.