Table 2.

Summary of findings for pregnancy subgroup: utility, RIO, or health state value information

Health state/outcome (categories of values and preferences)Estimates of utilitiesCertainty in evidenceInterpretation of findings
No. of participants/studies
Pregnancy-related DVT (Bates et al24 VAS: 46 (IQR, 30-65) ⊕⊕○○
Low certainty due to inconsistency and imprecision*, 
Women might possibly find pregnancy-related DVT having an important impact on their lives. There is likely an important variability for this assessment. 
123 participants from 1 study based on VAS 
Pregnancy-related PE (Bates et al24 VAS: 30 (IQR, 15-50) ⊕⊕○○
Low certainty due to inconsistency and imprecision*, 
Most women might possibly find pregnancy-related PE having an important impact on their lives. There is likely an important variability for this assessment. 
123 participants from 1 study based on VAS 
Obstetric bleeding (Bates et al24 VAS: 30 (IQR, 15-50) ⊕⊕○○
Low certainty due to inconsistency and imprecision*, 
Most women might possibly find obstetric bleeding having an important impact on their lives. There is likely an important variability. 
123 participants from 1 study based on VAS 
Treatment with LMWH (Bates et al24 Visual analog scale: 83 (IQR, 70-90) ⊕⊕⊕○
Moderate certainty due to imprecision 
Women may probably find treatment with LMWH having a small impact on their lives. There is some variability for this assessment. 
123 participants from 1 study based on VAS 
Health state/outcome (categories of values and preferences)Estimates of utilitiesCertainty in evidenceInterpretation of findings
No. of participants/studies
Pregnancy-related DVT (Bates et al24 VAS: 46 (IQR, 30-65) ⊕⊕○○
Low certainty due to inconsistency and imprecision*, 
Women might possibly find pregnancy-related DVT having an important impact on their lives. There is likely an important variability for this assessment. 
123 participants from 1 study based on VAS 
Pregnancy-related PE (Bates et al24 VAS: 30 (IQR, 15-50) ⊕⊕○○
Low certainty due to inconsistency and imprecision*, 
Most women might possibly find pregnancy-related PE having an important impact on their lives. There is likely an important variability for this assessment. 
123 participants from 1 study based on VAS 
Obstetric bleeding (Bates et al24 VAS: 30 (IQR, 15-50) ⊕⊕○○
Low certainty due to inconsistency and imprecision*, 
Most women might possibly find obstetric bleeding having an important impact on their lives. There is likely an important variability. 
123 participants from 1 study based on VAS 
Treatment with LMWH (Bates et al24 Visual analog scale: 83 (IQR, 70-90) ⊕⊕⊕○
Moderate certainty due to imprecision 
Women may probably find treatment with LMWH having a small impact on their lives. There is some variability for this assessment. 
123 participants from 1 study based on VAS 

Moderate certainty in evidence: We are moderately confident in the effect estimate; the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different. Low certainty in evidence: Our confidence in the effect estimate is limited; the true effect may be substantially different from the estimate of the effect.

IQR, interquartile range; VAS, visual analog scale.

*

Inconsistency due to important variability.

Imprecision due to small sample size.

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