Distribution of type I and type III IP3R as determined by immunogold labeling
| Antibody . | Gold particles/cell means ± SE . | Paired t test (Pvalues) . | |
|---|---|---|---|
| IM vs PM . | R26 PM vs . | ||
| R26 (type I) | |||
| IM | 6.33 ± 0.76 (15) | ||
| PM | 1.4 ± 0.32 (15) | .001 | |
| R45 (type III) | |||
| IM | 3.06 ± 0.36 (16) | ||
| PM | 2.58 ± 0.36 (16) | .283 | .047 |
| CT3 (type III) | |||
| IM | 4.53 ± 0.63 (15) | ||
| PM | 4.07 ± 0.58 (15) | .41 | .0013 |
| Antibody . | Gold particles/cell means ± SE . | Paired t test (Pvalues) . | |
|---|---|---|---|
| IM vs PM . | R26 PM vs . | ||
| R26 (type I) | |||
| IM | 6.33 ± 0.76 (15) | ||
| PM | 1.4 ± 0.32 (15) | .001 | |
| R45 (type III) | |||
| IM | 3.06 ± 0.36 (16) | ||
| PM | 2.58 ± 0.36 (16) | .283 | .047 |
| CT3 (type III) | |||
| IM | 4.53 ± 0.63 (15) | ||
| PM | 4.07 ± 0.58 (15) | .41 | .0013 |
Gold particles were counted for 15 (R26, CT3) or 16 (R45) cells and assigned to either PM (including open canalicular system) or IM structures. Means ± SE are noted, and paired t tests were analyzed using Stat-View software for IM vs PM for each antibody and R26 PM vs R45 PM or CT3 PM. P < .05 indicates statistical significance.