MTX and MP AUC and Erythrocyte TGN Level in Girls (n = 37) and Boys (n = 52)
| . | Girls4-150 . | Boys4-150 . | P Value . |
|---|---|---|---|
| Age (yr) | 4.1 (1.6-13.8) | 4.9 (1.1-17.3) | |
| MTX dose (mg/m2) | 18 (9.5-21) | 18 (3.8-23) | .25 |
| MTX AUC (μmol · h/L) | 4.0 (1.9-12) | 3.0 (1.1-9.4) | .0074 |
| MP dose (mg/m2) | 66 (33-85) | 68 (18-99) | .28 |
| MP AUC (μmol · h/L) | 1.7 (0.39-4.2) | 1.6 (0.26-8.0) | .71 |
| RBC TGN (pmol/g hgb) | 2.0 (0.16-8.2) | 1.8 (0.32-7.2) | .47 |
| . | Girls4-150 . | Boys4-150 . | P Value . |
|---|---|---|---|
| Age (yr) | 4.1 (1.6-13.8) | 4.9 (1.1-17.3) | |
| MTX dose (mg/m2) | 18 (9.5-21) | 18 (3.8-23) | .25 |
| MTX AUC (μmol · h/L) | 4.0 (1.9-12) | 3.0 (1.1-9.4) | .0074 |
| MP dose (mg/m2) | 66 (33-85) | 68 (18-99) | .28 |
| MP AUC (μmol · h/L) | 1.7 (0.39-4.2) | 1.6 (0.26-8.0) | .71 |
| RBC TGN (pmol/g hgb) | 2.0 (0.16-8.2) | 1.8 (0.32-7.2) | .47 |
Abbreviation: RBC TGN, erythrocyte TGN level.
Values represent the median and range of the mean parameters from each patient.