Plasma MDA and Oxidation Indices and Lipid Antioxidants in LDL From β-Thalassemia Patients and Control Subjects
| . | Controls n = 35 . | β-Thalassemia n = 35 . |
|---|---|---|
| Plasma MDA (μmol/L) | 0.90 ± 0.28 | 1.80 ± 0.59* |
| LDL-conjugated dienes (nmol/mg LDL prot) | 6.25 ± 3.04 | 22.60 ± 12.84* |
| Apo B lysine residues (nmol/mg LDL prot) | 500 ± 12 | 416 ± 24* |
| LDL-Vitamin E (nmol/mg LDL prot) | 13.83 ± 3.63 | 6.31 ± 3.21* |
| LDL-β-carotene (nmol/mg LDL prot) | 0.66 ± 0.2 | 0.16 ± 0.12* |
| . | Controls n = 35 . | β-Thalassemia n = 35 . |
|---|---|---|
| Plasma MDA (μmol/L) | 0.90 ± 0.28 | 1.80 ± 0.59* |
| LDL-conjugated dienes (nmol/mg LDL prot) | 6.25 ± 3.04 | 22.60 ± 12.84* |
| Apo B lysine residues (nmol/mg LDL prot) | 500 ± 12 | 416 ± 24* |
| LDL-Vitamin E (nmol/mg LDL prot) | 13.83 ± 3.63 | 6.31 ± 3.21* |
| LDL-β-carotene (nmol/mg LDL prot) | 0.66 ± 0.2 | 0.16 ± 0.12* |
Values are the mean ± SD of determinations performed in duplicate on blood samples and homologous LDL from different subjects. Each thalassemia patient contributed the mean of two values measured during 1 year of observation.
With respect to the relevant control, values were significant withP < .001 (Student’s t-test).