Characteristics of aplastic anemia patients given cyclophosphamide/antithymocyte globulin (CY/ATG) conditioning and HLA-matched related grafts. Data from Fred Hutchinson Cancer Research Center, Seattle VA Medical Center, Stanford University, and City of Hope.28
Patients studied, number of patients (n) | 94 |
Median age (range), yrs | 26 (2–59) |
Gender (F/M), n | 38/56 |
Possible causes, n | |
Unknown | 76 |
Hepatitis | 7 |
Pregnancy | 4 |
Drugs or chemicals | 5 |
Dyskeratosis congenita | 1 |
Fanconi anemia | 1 |
Transfused before transplant, % | 94 |
History of treatment, n | |
Antithymocyte globulin | 21 |
Cyclosporine | 22 |
Steroids | 32 |
Androgens | 11 |
Any immunosuppression | 38 |
Granulocyte colony-stimulating factor | 17 |
Median duration of aplastic anemia (range), mo | 2.4 (0.2–146.6) |
Patients studied, number of patients (n) | 94 |
Median age (range), yrs | 26 (2–59) |
Gender (F/M), n | 38/56 |
Possible causes, n | |
Unknown | 76 |
Hepatitis | 7 |
Pregnancy | 4 |
Drugs or chemicals | 5 |
Dyskeratosis congenita | 1 |
Fanconi anemia | 1 |
Transfused before transplant, % | 94 |
History of treatment, n | |
Antithymocyte globulin | 21 |
Cyclosporine | 22 |
Steroids | 32 |
Androgens | 11 |
Any immunosuppression | 38 |
Granulocyte colony-stimulating factor | 17 |
Median duration of aplastic anemia (range), mo | 2.4 (0.2–146.6) |