Table 6.

EPOCH regimen of infusional chemotherapy.

  • Etoposide 50 mg/m2/day × 4 days

  • Vincristine 0.4 mg/m2/day × 4 days

  • Doxorubicin 10 mg/m2/day × 4 days

  • Cyclophosphamide 187 mg/m2 IV on day 5 for CD4+ < 100 cells/mm3 or 375 mg/m2 IV on day 5 for CD4+ >/= 100 cells/mm3

  • Prednisone 60 mg/m2 orally, days 1–5

  • Granulocyte colony-stimulating factor (G-CSF): start on day 6

  • Repeat on day 22 times 6 cycles

 

  • Etoposide 50 mg/m2/day × 4 days

  • Vincristine 0.4 mg/m2/day × 4 days

  • Doxorubicin 10 mg/m2/day × 4 days

  • Cyclophosphamide 187 mg/m2 IV on day 5 for CD4+ < 100 cells/mm3 or 375 mg/m2 IV on day 5 for CD4+ >/= 100 cells/mm3

  • Prednisone 60 mg/m2 orally, days 1–5

  • Granulocyte colony-stimulating factor (G-CSF): start on day 6

  • Repeat on day 22 times 6 cycles

 
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