Baseline characteristics in 1638 patients with polycythemia vera recruited in the ECLAP Project.
Demographics . | n . |
---|---|
* For continuous variables, values are mean ± SD. | |
Age at recruitment (years) | 65.4 (12.7)* |
Males | 942 (57.5) |
Body mass index, kg/m2 | 25.4 (3.7)* |
Age at diagnosis (years) | 60.4 (13.2) |
Years from diagnosis to enrollment | |
0–2 | 581 (35.5) |
3–5 | 434 (26.5) |
6–10 | 387 (23.6) |
> 10 | 236 (14.4) |
Prior cardiovascular events | |
Prior thrombosis | 633 (38.6) |
Prior arterial thrombosis | 470 (28.7) |
AMI | 146 (8.9) |
Stroke | 145 (8.9) |
Transient ischemic attack | 169 (10.3) |
Peripheral | 90 (5.5) |
Prior venous thrombosis | 225 (13.7) |
Deep vein thrombosis | 134 (8.4) |
Pulmonary embolism | 39 (2.4) |
Superficial thrombophlebitis | 100 (6.1) |
Erythromelalgia | 86 (5.3) |
Intermittent claudication | 77 (4.7) |
Prior bleeding | 133 (8.1) |
Packed cell volume (l/l) | 0.47 (0.06)* |
Packed cell volume (l/l) | |
≤ 0.45 | 556 (38.9) |
0.46–0.50 | 530 (37.0) |
> 0.50 | 345 (24.1) |
Platelet count (×109/L) | 398 (208)* |
White blood cell count (×109/L) | 10.9 (8.6)* |
Antiplatelet drugs | 955 (58.3) |
Cytoreductive treatments | |
Phlebotomy | 1040 (63.5) |
Any cytoreductive drug | 1009 (61.6) |
Hydroxyurea | 793 (48.4) |
Pipobroman | 106 (6.5) |
Interferon | 64 (3.9) |
Busulfan | 61 (3.7) |
32P | 44 (2.7) |
Chlorambucil | 5 (0.3) |
Demographics . | n . |
---|---|
* For continuous variables, values are mean ± SD. | |
Age at recruitment (years) | 65.4 (12.7)* |
Males | 942 (57.5) |
Body mass index, kg/m2 | 25.4 (3.7)* |
Age at diagnosis (years) | 60.4 (13.2) |
Years from diagnosis to enrollment | |
0–2 | 581 (35.5) |
3–5 | 434 (26.5) |
6–10 | 387 (23.6) |
> 10 | 236 (14.4) |
Prior cardiovascular events | |
Prior thrombosis | 633 (38.6) |
Prior arterial thrombosis | 470 (28.7) |
AMI | 146 (8.9) |
Stroke | 145 (8.9) |
Transient ischemic attack | 169 (10.3) |
Peripheral | 90 (5.5) |
Prior venous thrombosis | 225 (13.7) |
Deep vein thrombosis | 134 (8.4) |
Pulmonary embolism | 39 (2.4) |
Superficial thrombophlebitis | 100 (6.1) |
Erythromelalgia | 86 (5.3) |
Intermittent claudication | 77 (4.7) |
Prior bleeding | 133 (8.1) |
Packed cell volume (l/l) | 0.47 (0.06)* |
Packed cell volume (l/l) | |
≤ 0.45 | 556 (38.9) |
0.46–0.50 | 530 (37.0) |
> 0.50 | 345 (24.1) |
Platelet count (×109/L) | 398 (208)* |
White blood cell count (×109/L) | 10.9 (8.6)* |
Antiplatelet drugs | 955 (58.3) |
Cytoreductive treatments | |
Phlebotomy | 1040 (63.5) |
Any cytoreductive drug | 1009 (61.6) |
Hydroxyurea | 793 (48.4) |
Pipobroman | 106 (6.5) |
Interferon | 64 (3.9) |
Busulfan | 61 (3.7) |
32P | 44 (2.7) |
Chlorambucil | 5 (0.3) |