Table 6.

Baseline characteristics in 1638 patients with polycythemia vera recruited in the ECLAP Project.

Demographicsn
* For continuous variables, values are mean ± SD. 
Age at recruitment (years) 65.4 (12.7)* 
Males 942 (57.5) 
Body mass index, kg/m2 25.4 (3.7)* 
Age at diagnosis (years) 60.4 (13.2) 
Years from diagnosis to enrollment 
    0–2 581 (35.5) 
    3–5 434 (26.5) 
    6–10 387 (23.6) 
    > 10 236 (14.4) 
Prior cardiovascular events 
Prior thrombosis 633 (38.6) 
Prior arterial thrombosis 470 (28.7) 
    AMI 146 (8.9) 
    Stroke 145 (8.9) 
    Transient ischemic attack 169 (10.3) 
    Peripheral 90 (5.5) 
Prior venous thrombosis 225 (13.7) 
    Deep vein thrombosis 134 (8.4) 
    Pulmonary embolism 39 (2.4) 
    Superficial thrombophlebitis 100 (6.1) 
Erythromelalgia 86 (5.3) 
Intermittent claudication 77 (4.7) 
Prior bleeding 133 (8.1) 
Packed cell volume (l/l) 0.47 (0.06)* 
Packed cell volume (l/l) 
    ≤ 0.45 556 (38.9) 
    0.46–0.50 530 (37.0) 
    > 0.50 345 (24.1) 
Platelet count (×109/L) 398 (208)* 
White blood cell count (×109/L) 10.9 (8.6)* 
Antiplatelet drugs 955 (58.3) 
Cytoreductive treatments 
Phlebotomy 1040 (63.5) 
Any cytoreductive drug 1009 (61.6) 
    Hydroxyurea 793 (48.4) 
    Pipobroman 106 (6.5) 
    Interferon 64 (3.9) 
    Busulfan 61 (3.7) 
    3244 (2.7) 
    Chlorambucil 5 (0.3) 
Demographicsn
* For continuous variables, values are mean ± SD. 
Age at recruitment (years) 65.4 (12.7)* 
Males 942 (57.5) 
Body mass index, kg/m2 25.4 (3.7)* 
Age at diagnosis (years) 60.4 (13.2) 
Years from diagnosis to enrollment 
    0–2 581 (35.5) 
    3–5 434 (26.5) 
    6–10 387 (23.6) 
    > 10 236 (14.4) 
Prior cardiovascular events 
Prior thrombosis 633 (38.6) 
Prior arterial thrombosis 470 (28.7) 
    AMI 146 (8.9) 
    Stroke 145 (8.9) 
    Transient ischemic attack 169 (10.3) 
    Peripheral 90 (5.5) 
Prior venous thrombosis 225 (13.7) 
    Deep vein thrombosis 134 (8.4) 
    Pulmonary embolism 39 (2.4) 
    Superficial thrombophlebitis 100 (6.1) 
Erythromelalgia 86 (5.3) 
Intermittent claudication 77 (4.7) 
Prior bleeding 133 (8.1) 
Packed cell volume (l/l) 0.47 (0.06)* 
Packed cell volume (l/l) 
    ≤ 0.45 556 (38.9) 
    0.46–0.50 530 (37.0) 
    > 0.50 345 (24.1) 
Platelet count (×109/L) 398 (208)* 
White blood cell count (×109/L) 10.9 (8.6)* 
Antiplatelet drugs 955 (58.3) 
Cytoreductive treatments 
Phlebotomy 1040 (63.5) 
Any cytoreductive drug 1009 (61.6) 
    Hydroxyurea 793 (48.4) 
    Pipobroman 106 (6.5) 
    Interferon 64 (3.9) 
    Busulfan 61 (3.7) 
    3244 (2.7) 
    Chlorambucil 5 (0.3) 

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