Table 4.

Hematological and molecular complete response (CR) rates after induction in adult ALL.a

SensitivityHematologic CRb < 102Molecular CRc < 104Molecular CRd < 104 and negative
a Results of GMALL (German Multicenter Studies for Adult ALL) studies.33– 35  
b Morphological explanation 
c Minimal residual disease (MRD) level below 104, positive or negative (minimum sensitivity 104
d No detectable MRD at a sensitivity below 104 
Overall 82%   
Standard risk    
    B Lineage 88% 78% 41% 
    T Lineage 87% 82% 64% 
High risk 83%   
Ph/BCR-ABL 77% 18% 4% 
SensitivityHematologic CRb < 102Molecular CRc < 104Molecular CRd < 104 and negative
a Results of GMALL (German Multicenter Studies for Adult ALL) studies.33– 35  
b Morphological explanation 
c Minimal residual disease (MRD) level below 104, positive or negative (minimum sensitivity 104
d No detectable MRD at a sensitivity below 104 
Overall 82%   
Standard risk    
    B Lineage 88% 78% 41% 
    T Lineage 87% 82% 64% 
High risk 83%   
Ph/BCR-ABL 77% 18% 4% 

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