Hematological and molecular complete response (CR) rates after induction in adult ALL.a
Sensitivity . | Hematologic CRb < 102 . | Molecular CRc < 104 . | Molecular CRd < 104 and negative . |
---|---|---|---|
a Results of GMALL (German Multicenter Studies for Adult ALL) studies.33– 35 | |||
b Morphological explanation | |||
c Minimal residual disease (MRD) level below 104, positive or negative (minimum sensitivity 104) | |||
d No detectable MRD at a sensitivity below 104 | |||
Overall | 82% | ||
Standard risk | |||
B Lineage | 88% | 78% | 41% |
T Lineage | 87% | 82% | 64% |
High risk | 83% | ||
Ph/BCR-ABL | 77% | 18% | 4% |
Sensitivity . | Hematologic CRb < 102 . | Molecular CRc < 104 . | Molecular CRd < 104 and negative . |
---|---|---|---|
a Results of GMALL (German Multicenter Studies for Adult ALL) studies.33– 35 | |||
b Morphological explanation | |||
c Minimal residual disease (MRD) level below 104, positive or negative (minimum sensitivity 104) | |||
d No detectable MRD at a sensitivity below 104 | |||
Overall | 82% | ||
Standard risk | |||
B Lineage | 88% | 78% | 41% |
T Lineage | 87% | 82% | 64% |
High risk | 83% | ||
Ph/BCR-ABL | 77% | 18% | 4% |