Table 7.

Maximal paraprotein decline with PS-341 alone.

ITT Population (n = 70)*n (%)Cumulative (%)
* 8 patients with either nonsecretory myeloma or missing data. 
Complete or partial response 
    >90% reduction 14 (20) 20 
    ≥75% reduction 7(10) 30 
    ≥50% reduction 6 (9) 39 
    ≥25 reduction 6 (9) 47 
No change 21 (30) 77 
PD (≥25% increase) 12 (17)  
Non-evaluable 4 (6)  
ITT Population (n = 70)*n (%)Cumulative (%)
* 8 patients with either nonsecretory myeloma or missing data. 
Complete or partial response 
    >90% reduction 14 (20) 20 
    ≥75% reduction 7(10) 30 
    ≥50% reduction 6 (9) 39 
    ≥25 reduction 6 (9) 47 
No change 21 (30) 77 
PD (≥25% increase) 12 (17)  
Non-evaluable 4 (6)  

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